منابع مشابه
Right ventricular pressure and dilation during pressure overload determine dysfunction after pressure overload.
Volume expansion and inotropic stimulation are used clinically to augment cardiac output during acute right ventricular (RV) pressure overload. We previously showed that a brief period of RV pressure overload causes RV free wall dysfunction that persists after normal loading conditions have been restored. However, the impact of volume expansion and inotropic stimulation on the severity of RV dy...
متن کاملChronic Pressure Overload
Left ventricular (LV) function during the adaptation to chronic pressure overload produced by an ascending aortic constriction was analyzed in conscious dogs, instrumented with intraventricular micromanometers and pairs of ultrasonic crystals for measurement of LV wall thickness (WTh) and internal LV chamber diameter. During inflation of the cuff to produce LV pressures averaging 220 mm Hg, cal...
متن کاملHearts With Pressure-Overload Hypertrophy
Serial changes in left ventricular (LV) size and function during the adaptation to chronic pressure overload and the transition to pump failure were studied in 16 conscious dogs (aortic bands placed at 8 weeks of age). Echocardiographic data at baseline and at 3, 6, 9, and 12 months after banding revealed a progressive increase in LV mass in all dogs. In six dogs with LV pump failure, there was...
متن کاملEffect of Chronic Pressure and Volume Overload
I NCREASE in chamber volume (and therefore increase in wall surface area) is an appropriate adaptation to an increased volume load.' Conversely, a small thick-walled chamber is better suited to deal with a pressure load.2-4 That the human heart so adapts itself to chronic volume and chronic pressure loads is evident from clinical experience and postmortem studies. However, actual measurements o...
متن کاملTOLL-erating cardiac hypertrophy following pressure overload.
Sensing and defeating microbial infections are essential to the survival of metazoan species and contingent upon the reliable detection of pathogens, which are characterized by rapid evolution and molecular heterogeneity. Multicellular species have developed two overall strategies to kill and remove parasites, to send them ‘‘floating on the Stygian river’’ (after the river Styx in Hades, the un...
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ژورنال
عنوان ژورنال: British Dental Journal
سال: 2020
ISSN: 0007-0610,1476-5373
DOI: 10.1038/s41415-020-1601-z